Binary-blend fibber-based capture assay of circulating tumor cells for clinical diagnosis of colorectal cancer
نویسندگان
چکیده
منابع مشابه
Binary-blend fibber-based capture assay of circulating tumor cells for clinical diagnosis of colorectal cancer
BACKGROUND In addition to conventional approaches, detecting and characterizing CTCs in patient blood allows for early diagnosis of cancer metastasis. METHODS We blended poly(ethylene oxide) (PEO) into nylon-6 through electrospinning to generate a fibrous matbased circulating tumour cells (CTCs) assay. The contents of nylon-6 and PEO in the electrospun blend fibrous mats (EBFMs) were optimize...
متن کاملCirculating tumor cells of colorectal cancer
As the prognosis of colorectal cancer (CRC) patients is mostly determined by the occurrence of distant metastases, circulating tumor cells (CTC) may be an attractive therapeutic target. Despite the rarity of CRCderived CTC, considerable progress has recently been made in the investigation of their molecular characteristics. In this review article we present recent clinical and molecular data on...
متن کاملCirculating Tumor Cells In Colorectal Cancer.
The significance of circulating tumor cells (CTCs) has been discussed for more than a century. The advent of modern technology has allowed for more reliable detection of CTCs, and recent studies have provided compelling evidence that CTCs predict clinical response in metastatic colorectal cancer (mCRC). Combination of CTC analysis with independent prognostic factors has demonstrated powerful sy...
متن کاملCapture of viable circulating tumor cells in the liver of colorectal cancer patients.
BACKGROUND The incidence and number of circulating tumor cells (CTCs) in the peripheral blood of colorectal cancer patients are lower than in other cancer types, which may point to a particular biology of colorectal cancer affecting CTC detection. METHODS We detected CTCs in the peripheral and mesenteric blood of colorectal cancer patients by use of 2 independent technologies on the basis of ...
متن کاملInertia based microfluidic capture and characterisation of circulating tumour cells for the diagnosis of lung cancer.
BACKGROUND Routine clinical application of circulating tumour cells (CTCs) for blood based diagnostics is yet to be established. Despite growing evidence of their clinical utility for diagnosis, prognosis and treatment monitoring, the efficacy of a robust platform and universally accepted diagnostic criteria remain uncertain. We evaluate the diagnostic performance of a microfluidic CTC isolatio...
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ژورنال
عنوان ژورنال: Journal of Nanobiotechnology
سال: 2018
ISSN: 1477-3155
DOI: 10.1186/s12951-017-0330-1